Prisma Access
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Compatibility Matrix

Prisma Access

Table of Contents

Prisma Access

Learn about compatibility information for Prisma® Access.
The following topics provide support information for Prisma® Access:

What Features Does Prisma Access Support?

These sections provide you with the supported features and network settings for Prisma Access (both Prisma Access (Managed by Strata Cloud Manager) and Prisma Access (Managed by Panorama)).
For a description of the features supported in GlobalProtect™, see the features that GlobalProtect supports.

Management

FeaturePrisma Access (Managed by Strata Cloud Manager)Prisma Access (Managed by Panorama)
Best Practice Checks
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Default Configurations
Default settings enable you to get started quickly and securely
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Examples include:
  • Default DNS settings
  • Default GlobalProtect settings, including for the Prisma Access portal
  • Default Prisma Access infrastructure settings
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Built-in Best Practice Rules
To ensure that your network is as secure as possible, enable your users and applications based on best practice templates. With best practices as your basis, you can then refine policy based on your enterprise needs.
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Features with best practice rules include:
  • Security rules
  • Security profiles
  • Decryption
  • M365
—
Onboarding Walkthroughs for First-Time Setup
Guided walkthroughs include:
  • Onboard Remote Networks
  • Onboard Mobile Users (GlobalProtect)
  • Onboard Your HQ or Data Centers
  • Turn on Decryption
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Centralized Management Dashboards
These can include best practice scores and usage information
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Dashboards are available for features including:
  • Security Policy
  • Security Profiles
  • Decryption
  • Authentication
  • Certificates
  • SaaS Application Management
—
Hit Counts
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Hit counts for Security profiles include counts that measure the profile’s effectiveness, and these can depend on the profile (for example, unblocked critical and high severity vulnerabilities, or WildFire submission types).
Policy Rule Usage
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Profile Groups
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Remote Networks

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
IPSec Tunnels
We do not support FQDNs for peer IPSec addresses; use an IP address for the peer address instead.
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Secure Inbound Access
Tunnel Monitoring
Dead Peer Detection (DPD)
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ICMP
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Bidirectional Forwarding Detection (BFD)
—
—
SNMP
Use Tunnel Monitoring instead of SNMP to monitor the tunnels in Prisma Access.
—
—

Service Connections

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
IPSec Tunnels
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We do not support FQDNs for peer IPSec addresses; use an IP address for the peer address instead.
Tunnel Monitoring
Dead Peer Detection (DPD)
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ICMP
√
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Bidirectional Forwarding Detection (BFD)
—
—
SNMP
Use Tunnel Monitoring instead of SNMP to monitor the tunnels in Prisma Access.
—
—
Traffic Steering
(using policy-based forwarding rules to forward internet-bound traffic to service connections)
Introduced in 1.7.

Mobile Users—GlobalProtect

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Using On-Premises Gateways (Hybrid Deployments)
On-premises gateway integration with Prisma Access
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We support using on-premises gateways with Prisma Access gateways.
Priorities for Prisma Access and On-Premises Gateways
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Supported for deployments that have on-premises GlobalProtect gateways. You can set a priority separately for on-premises gateways and collectively for all gateways in Prisma Access. You can also specify source regions for on-premises gateways.
Manual Gateway Selection
Users can manually select a cloud gateway from their client machines using the GlobalProtect app.
GlobalProtect Gateway Modes
External Mode
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Introduced in 5.1 Preferred and Innovation.
If you are running a version below 5.1 Innovation, you can add one or more on-premise gateways and configure them as internal gateways.
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Introduced in 5.1 Preferred and Innovation.
If you are running a version below 5.1 Innovation, you can add one or more on-premise gateways and configure them as internal gateways.
GlobalProtect App Connect Methods
User-Logon (always on)
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Pre-Logon (always on)
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Pre-Logon (then on-demand)
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On-Demand
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Clientless VPN
Clientless VPN
Mobile User—GlobalProtect Features
Support for Mutliple Username Formats
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Mobile Device Management (MDM)
—
MDM Integration with HIP
Prisma Access does not support AirWatch MDM HIP service integration; however, you can use the GlobalProtect App for iOS and Android MDM Integration for HIP-Based Policy Enforcement
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Optimized Split Tunneling for GlobalProtect
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Administratively Log Out Mobile Users
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Introduced in 1.4.
DHCP
Prisma Access uses the IP address pools you specify during mobile user setup to assign IP addresses to mobile users and does not use DHCP.
—
—
GlobalProtect App Version Controls
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One-click configuration for GlobalProtect agent log collection

Prisma Access Explicit Proxy

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Explicit Proxy Support
Introduced in 2.0 Innovation.
Explicit Proxy Connectivity in GlobalProtect for Always-On Internet Security
Introduced in 4.0 Preferred with GlobalProtect app version 6.2
Introduced in 4.0 Preferred with GlobalProtect app version 6.2

Cloud-Delivered Security Services (CDSS)

Feature
Prisma Access (Managed by Strata Cloud Manager)Prisma Access (Managed by Panorama)
Advanced DNS Security Powered by Precision AI®:
DNS Hijacking and Misconfiguration Prevention√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Meticulously detects and immediately blocks DNS hijacking (where attackers alter DNS records to redirect traffic) and accidental or malicious DNS misconfigurations. This ensures the integrity of DNS resolution by preventing unauthorized redirection through advanced monitoring and analysis.
Malicious Traffic Distribution System (TDS)√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Combats threats hidden within malicious TDS—sophisticated attack frameworks that use complex DNS schemes to distribute malware and exploit kits. The service analyzes DNS traffic patterns to identify indicators of compromise (IOCs), effectively blocking access to these malicious distribution channels.
Domain Masquerading Protection√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Safeguards against domain masquerading by identifying and blocking malicious domains that closely resemble legitimate ones (typosquatting). It uses cutting-edge AI and machine learning algorithms to analyze vast amounts of DNS data, detecting subtle patterns and characteristic behaviors associated with spoofed or malicious domains.
Advanced URL Filtering
Compromised Website√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
This category specifically identifies legitimate websites that have been hacked or infected with malicious content. This allows you to use granular policy control to distinguish between inherently malicious sites and otherwise trustworthy sites that have been temporarily compromised.
File Converter√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
This categorizes sites that allow users to convert, compress, or modify files. This new category helps organizations manage access to these tools, mitigating data leakage and compliance risks associated with unauthorized file sharing and modification.
ML-powered Quishing (QR Code) Protection√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Blocks quishing attacks by introducing an ML-powered QR code detector. This feature specifically addresses the growing threat of malicious QR codes embedded on legitimate websites, which attackers use to bypass the perimeter defenses of enterprise-protected networks and target unmanaged personal devices.
Deepfake Content Detection√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Protects against hyper-realistic social engineering. A new deep learning model is active to identify and block malicious content featuring deepfake videos. This provides essential protection from attackers who use highly convincing deepfake impersonations of trusted individuals in phishing attacks.
Advanced WildFire® Powered by Precision AI
PDF Analysis for Phishing√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
A Convolutional Neural Network (CNN)-based deep learning model is available. This model analyzes the visual appearance (in addition to the text) of embedded URLs in PDF files to detect highly evasive, embedded phishing attacks that exploit the PDF format.
API Vector Categorization√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Leverages Machine Learning (ML) to perform in-memory analysis of the patterns and sequences of API calls made by malware during runtime. This advanced approach creates a unique behavioral "fingerprint" (API Vector) to accurately identify and classify highly evasive, fileless, and memory-resident attacks that bypass conventional analysis.
Multi-CPU advanced dynamic analysis√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Enhances Advanced Dynamic Analysis (sandboxing) by including multiple virtual CPUs (vCPUs) in the Windows guest sandbox environment. This capability is specifically designed to defeat sophisticated malware that evades detection by checking for and refusing to execute in single-CPU virtual environments.
Advanced Threat Prevention Powered by Precision AI
Exfiltration Shield for Advanced Threat Prevention√
Minimum dataplane version of PAN-OS® 11.2 required
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Minimum Cloud Services plugin of 6.0 and minimum dataplane version of PAN-OS® 11.2 required
Uses a sophisticated machine learning (ML) model to combat advanced data exfiltration. This feature focuses on detecting stealthy data egress over common protocols like DNS relay and HTTP headers, which are frequently used to bypass traditional security. Integration is seamless with existing Advanced DNS Security and ATP subscriptions.

Security Services

Feature
Prisma Access (Managed by Strata Cloud Manager)Prisma Access (Managed by Panorama)
Security Policy
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DoS Protection
The Prisma Access infrastructure manages DoS protection.
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SaaS Application Management
Supported for:
  • Microsoft 365 apps
    Includes a guided walkthrough to safely enable M365
  • Google apps
  • Dropbox
  • YouTube
—
IoT Security
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Security Profiles
Supported Profile Types
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  • Antispyware
  • DNS Security
  • Vulnerability Protection
  • WildFire and Antivirus
  • URL Filtering
    Domain Credential Filter detection is not supported with URL filtering.
  • File Blocking
  • Data Loss Prevention (DLP)
  • HTTP Header Insertion
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  • Antispyware
  • DNS Security (enabled via an Antispyware profile)
  • Vulnerability Protection
  • Antivirus
  • WildFire
  • URL Filtering
    Domain Credential Filter detection is not supported with URL filtering.
  • File Blocking
  • Data Loss Prevention (DLP)
Dashboards for Security Profiles
Dashboards are tailored to each profile, and give you:
  • centralized management for security service features
  • visibility into profile usage and effectiveness
  • access to cloud databases (search for threat coverage, for example)
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Best Practice Scores for Security Profiles
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We support HTTP response pages for mobile users and users at remote networks. To use HTTPS response pages, open a CLI session in the Panorama that manages Prisma Access, enter the set template Mobile_User_Template config deviceconfig settingssl-decrypt url-proxyyes command in configuration mode, and commit your changes.
HTTP Header Insertion
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Decryption
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SSL Forward Proxy
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SSL Inbound Inspection
—
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SSH Proxy
—
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Guided Walkthrough:
Turn on Decryption
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Network Services

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Network Services
Prisma Access uses the same QoS policy rules and QoS profiles and supports the same DSCP markings as Palo Alto Networks Next-Generation Firewalls.
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Application Override
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IPv4 Addressing
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IPv6 addressing for private apps introduced in 2.2 Preferred; IPv6 addressing for public (internet) and private apps introduced in 5.2.1.
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Split Tunnel Based on Access Route
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Split Tunnel Based on Destination Domain, Client Process, and Video Streaming Application
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NetFlow
—
—
NAT
Prisma Access automatically manages outbound NAT; you cannot configure the settings.
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SSL VPN Connections
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Routing Features
Static Routing
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Dynamic Routing (BGP)
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Dynamic Routing (OSPF)
—
—
High Availability
Palo Alto Networks maintains Availability.
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SMTP
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Prisma Access sometimes blocks SMTP port 25 for security reasons and to mitigate the risk from known vulnerabilities that exploit nonsecure SMTP. Palo Alto Networks recommends using ports 465, 587, or an alternate port 2525 for SMTP.
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Prisma Access sometimes blocks SMTP port 25 for security reasons and to mitigate the risk from known vulnerabilities that exploit nonsecure SMTP. Palo Alto Networks recommends using ports 465, 587, or an alternate port 2525 for SMTP.

Identity Services

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Authentication Types
SAML
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TACACS+
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RADIUS
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LDAP
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Kerberos
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We support Kerberos only on Windows clients.
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Kerberos SSO
MFA
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Local Database Authentication
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Authentication Features
Authentication Rules
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Authentication Portal
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Supported for both IPSec and mobile users with GlobalProtect.
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Supported for both IPSec and mobile users with GlobalProtect.
—
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Framed IP-Address retrieval from a RADIUS server
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Extensible Authentication Protocol (EAP) Support for RADIUS
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Single Sign-On (SSO)
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Supported for the following platforms:
  • Citrix XenApp 7.x
  • Windows Server 2019
  • Windows 10 Enterprise Multi-session
We support a maximum of 1,000 TS agents.
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Supported for the following platforms:
  • Citrix XenApp 7.x
  • Windows Server 2019
  • Windows 10 Enterprise Multi-session
We support a maximum of 1,000 TS agents.
Cloud Identity Engine (Directory Sync Component)
Directory Sync for User and Group-Based Policy
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Supports on-premises Active Directory and Azure Active Directory.
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You can retrieve user and group information using the Directory Sync component of the Cloud Identity Engine.
Prisma Access supports on-premises Active Directory, Azure Active Directory, and Google IdP.
Introduced in 1.6.
Support for Azure Active Directory introduced in 2.0 Preferred.
Support for Google IdP introduced in 3.0 Preferred and Innovation.
Identity Redistribution
  • IP address-to-username mappings
  • HIP
  • Device Quarantine
  • IP-Tag
  • User-Tag
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Ingestion of IP address-to-username mappings from a third-party integration (NAC)
—
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Introduced in 1.7.
Requires Panorama running a minimum PAN-OS 9.1.1 version.

Policy Objects

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Addresses
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Address Groups
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Dynamic Address Groups (DAGs) and Auto-Tags
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XML API - Based Dynamic Address Group Updates
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Regions
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App-ID (Applications)
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We do not support commit warnings for Prisma Access.
Service-Based Session Timeouts
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Application Groups
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Application Filters
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Services
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Service Groups
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Tags
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Introduced in 1.7.
Requires Panorama running a minimum PAN-OS 9.1.1 version.
Auto-Tag Actions
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HIP Objects
HIP
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HIP Match Log
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HIP-Based Security Policy
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HIP Notifications
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HIP Report Submission
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HIP Report Viewing
—
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Introduced in 1.5.
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Introduced in 1.5.
HIP Objects and Profiles
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External Dynamic Lists
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Certificate Management
Custom Certificates
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Palo Alto Networks Issued Certificates
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Certificate Profiles
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Custom Certificates
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SSL/TLS Service Profiles
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SSL
We support SSL only for mobile users, not for site-to-site VPNs.
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SCEPs
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OCSP Responders
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Default Trusted Certificate Authorities
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Logs

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
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Strata™ Logging Service (formerly Cortex® Data Lake) Log Storage
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Default Log Forwarding profile
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We do not support HTTP, SNMP, auto-tagging in Built-in Actions.
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Introduced in 1.7.
Requires Panorama running a minimum PAN-OS 9.1.1 version.

Reports

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Reports
You can also use Dashboards for a comprehensive view of the applications, ION devices, threats, users, and security subscriptions at work in your network.
Introduced in Prisma Access 1.8.
App Report
This feature has the following Strata Logging Service-based limitation:
SaaS Application Usage report (MonitorPDF ReportsSaaS Application Usage)—You cannot filter the logs for user groups (we do not support the Include user group information in the report option).
Usage Report
User Activity Report
Best Practices Report
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WildFire Reports
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Support introduced in 2.0 Innovation.

Integration with Other Palo Alto Networks Products

Feature
Prisma Access (Managed by Strata Cloud Manager)
Prisma Access (Managed by Panorama)
Cortex XSOAR integration
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We support source IP-based allow lists and malicious user activity detection.
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Cortex XDR integration
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Prisma Access is compatible with the Cortex XDR version of Strata Logging Service. Cortex XDR receives Prisma Access log information from Strata Logging Service (formerly Cortex Data Lake).
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Prisma Access is compatible with the Cortex XDR version of Strata Logging Service. Cortex XDR receives Prisma Access log information from Strata Logging Service (formerly Cortex Data Lake).
Prisma SaaS integration
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Panorama Managed Multitenant Unsupported Features and Functionality

Starting April 15, 2026, Panorama-based Prisma Access multi-tenancy will no longer be offered for new Prisma Access deployments. If you require multi-tenancy for new deployments after April 15, 2026, Palo Alto Networks strongly recommends that you use Prisma Access (Managed by Strata Cloud Manager), where you can manage tenants using Strata Multitenant Cloud Manager. If you currently use Panorama for multi-tenancy, your deployment continues to operate with full support with no required changes to your environments or day-to-day operations, and existing deployments remain fully supported. However, as innovation shifts toward next-generation platforms, certain future features introduced after April 15, 2026, may be available exclusively through the newer SCM management experience.
We do not support the following features in a Prisma Access (Managed by Panorama) multitenant deployment:
In addition, a Panorama managed multitenant deployment has changes to the following functionality:
  • You cannot view your Panorama managed tenants under Common Services: Tenant Management.
  • For Prisma Access (Managed by Panorama), continue to use Panorama for managing Prisma Access and the admin access that Panorama controls locally. You cannot manage users, roles, and services accounts using Common Services: Identity and Access for Prisma Access (Managed by Panorama). However, you can use Common Services: Identity and Access for managing other apps such as ADEM and Insights.
  • You cannot use the Prisma Access APIs in pan-dev.
The following Prisma Access components and add-ons have the following caveats when used in a multitenant deployment:
  • For the following components, if you have an existing Prisma Access (Managed by Panorama) non-multitenant deployment and convert it to a multitenant deployment, only the first tenant (the tenant you migrated) supports these components. Any subsequent tenants you create for the multitenant deployment after the first one do not support these components:
  • SaaS Security and Enterprise Data Loss Prevention (Enterprise DLP) support multitenancy with the following restrictions:
    • Only a superuser on Panorama can create DLP profiles and patterns and can associate DLP profiles to Security policy rules for tenants.
    • A superuser must commit all changes to Panorama whenever they make changes in DLP profiles and patterns.
    • All tenants share a single copy of profiles and pattern configurations and, therefore, changes occur on all tenants.
    • Since Security policy rules can be different across tenants, each tenant can have different data filtering profiles associated with Security policy rules.
  • If you enable high availability (HA) with active and passive Panorama appliances in a multitenant deployment, you cannot change the HA pair association after you enable multitenancy.
  • You can use these features with a Prisma Access (Managed by Panorama) multitenant deployment; however you can only use them in one tenant per multitenant deployment:

Prisma Access and Panorama Version Compatibility

This section provides you with the minimum and maximum versions of Panorama™ to use with Prisma® Access.

Minimum Required Panorama Software Versions

The Cloud Services plugins require the following minimum Panorama™ software versions.
For more information about the versions used with Prisma Access, including the recommended Panorama and GlobalProtect versions, see the Prisma Access Release Notes for your release:
Cloud Services Plugin VersionMinimum Required Panorama Version
6.2 Preferred and Innovation
  • 12.1.8
  • 11.2.0
  • 11.1.0
  • 11.0.1+
  • 10.2.10+
6.1 Preferred and Innovation
  • 12.1.2
  • 11.2.0
  • 11.1.0
  • 11.0.1
  • 10.2.10
6.0 Preferred and Innovation
5.2 and 5.2.1 Preferred and Innovation
  • PAN-OS 11.2.4 (the minimum version required for 5.2.1 Innovation)
  • PAN-OS 11.2.3 (the minimum version required for 5.2 Innovation)
  • PAN-OS 11.1.0
  • PAN-OS 11.0.1
  • PAN-OS 10.2.4 (the minimum version required for 5.2 and 5.2.1 Preferred)
5.1 and 5.1.1 Preferred and Innovation
  • PAN-OS 11.2 (the minimum version required for 5.1 and 5.1.1 Innovation)
  • PAN-OS 11.1.0
  • PAN-OS 11.0.1
  • PAN-OS 10.2.4 (the minimum version required for 5.1 and 5.1.1 Preferred)
4.0, 4.1, and 4.2 Preferred
5.0 and 5.0.1 Preferred and Innovation
  • PAN-OS 11.1.0
  • PAN-OS 11.0.0
    Running Panorama with PAN-OS 11.0 or PAN-OS 11.1 does not give you access to PAN-OS 11.0 features in Prisma Access.
  • PAN-OS 10.2.3
  • PAN-OS 10.1.7
    You must have a Panorama appliance running PAN-OS 10.2 to take advantage of the PAN-OS 10.2 features in Prisma Access.
For Panorama versions supported and required for FedRAMP deployments, see Prisma Access FedRAMP Requirements.

Supported IKE Cipher Suites

The following table documents the IKE cryptographic settings that we support with Prisma Access.
ComponentPhase 1 Supported Crypto ParametersPhase 2 Supported Crypto Parameters
Encryption
3des
aes-128-cbc
aes-192-cbc
aes-256-cbc
aes-128-gcm
aes-256-gcm
null (not recommended)
3des
aes-128-cbc
aes-192-cbc
aes-256-cbc
aes-128-gcm
aes-256-gcm
Authentication
non-auth
If you select an AES with Galois/Counter Mode (AES-GCM) algorithm for encryption, you must select the Authentication setting non-auth or the commit will fail. The hash is automatically selected based on the DH Group selected. DH Group 19 and below uses sha256; DH Group 20 uses sha384.
md5
sha1
sha256
sha384
sha512
md5
none
If you select an AES-GCM algorithm for encryption, you must select none for Phase 2 authentication or the commit will fail. The hash is automatically selected based on the DH Group selected. DH Group 19 and below uses sha256; DH Group 20 uses sha384.
sha1
sha256
sha384
sha512
DH Group
Group 1
Group 2
Group 5
Group 14
Group 19
Group 20
No PFS (not recommended)
Group 1
Group 2
Group 5
Group 14
Group 19
Group 20
Security Association (SA) Lifetime
Configurable
Configurable
SA Lifebytes
N/A
Configurable