If you have mission critical applications
that must be 100% available, set the threshold for Applications
or Applications and Threats updates to a minimum of 24 hours or
more and follow the
Best Practices for Applications and Threats Content Updates. Additionally,
While scheduling content updates is a one-time or infrequent task,
after you’ve set the schedule, you’ll need to continue to
Manage
New and Modified App-IDs that are included in content releases,
as these App-IDs can change how security policy is enforced.